Investigation of different solutions activated by air plasma jet and their anticancer effect

In the field of plasma biomedicine, research on a plasma-activated medium (PAM) has attracted increasing attention in recent years because its excellent characteristics. this study, we used an atmospheric pressure air jet to treat four different solutions: de-ionized water, RPMI 1640 medium, phosphate buffered saline (PBS), and saline. order investigate property differences PAM, mainly analyzed physical chemical properties liquid-phase active species PAM evaluated inactivation A549 lung cancer cells. The results show that concentrations long-lived reactive (H 2 O , NO ? 3 ) increased with treatment time. Biological experiments showed antitumor effects were PBS > best effect for 12 min was 89%. Meanwhile, effectively promoted apoptosis cells, highest rate 91.3%. Therefore, study demonstrates medical application killing cells promotes understanding plasma–liquid interaction.